Management of Anthrax

Executive Summary

Anthrax represents one of the greatest biowarfare threats. The recent occurrences of anthrax in United States of America, and the resultant panic have increased the awareness about the extreme difficulty in handling such threats in a coordinated manner. The infrastructure available in developing countries to meet this challenge is grossly inadequate with rudimentary technical expertise. No central agency for dealing with such outbreaks, or effectively coordinating the national activities against biowarfare exists in countries of South-East Asia Region. Accordingly, an Intercountry Workshop on Management of Anthrax was organized in collaboration with Centres for Disease Control and Prevention of USA (CDC) and Ministry of Public Health, Thailand (MOPH) at Bangkok from 6 to 8 December 2001. Epidemiologists and bacteriologists from nine countries of South East Asia Region and five countries of Western Pacific Region of WHO participated. Experts from India, CDC, MOPH, Regional Office for SEA and WHO/CSR Office in Lyons facilitated this workshop. The workshop was organized to upgrade the skills of the participants in investigation and control of an outbreak of anthrax.

 

The workshop was designed to have considerable interaction of facilitators with epidemiologists as well as bacteriologists. Specific sessions were organized for epidemiology, clinical presentations, case definitions, laboratory processing, chemoprophylaxis and investigation of outbreak. The activities also included lecture-discussions, panel discussions and demonstrations in the laboratory. A problem-solving session was also organized between the participants and an expert panel at CDC, Atlanta, USA through teleconference. Since most of the countries do not have any well developed plan of action to respond to the outbreaks of anthrax or any other potential biological weapon, the participants were guided to develop a plan of action. They were advised to finalize it in consultation with national authorities.

 

The workshop highlighted the inadequacies that exist in the state of preparedness of Member Countries against anthrax and bioterrorism. It was clearly emphasized by the CDC experts that processing of environmental samples can lead to aerosolization and such samples must never be handled unless containment facilities of biosafety level 3 (BSL-3) are available. Mere processing of clinical material may be undertaken in BSL-2 facilities.

 

The participants of the workshop recommended that each country must have a national action plan to meet this challenge, develop and maintain suitable infrastructure, adopt WHO guidelines for strengthening of their laboratory and epidemiological capabilities, train various categories of staff (physicians, public health professionals, bacteriologists, postal authorities, police etc) develop IEC material as well as mechanisms to utilize the mass media to prevent panic among communities and develop effective linkages with various laboratories within the country as well as outside.

 

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