World Health Organization Regional Office for South-East Asia

Media Centre – News 2010

Steady progress made towards treating TB in Timor-Leste

Dili: A greater number of new positive Tuberculosis (TB) cases are being detected now in Timor-Leste compared to nine years ago. Of these new cases, about 85% are being successfully treated. Timor Leste’s TB burden was first recorded in 1995 and averaged 707 cases per 100,000 of its population. Today it stands at 378 cases per 100,000 of its population. “Timor-Leste is on track to meeting the MDG goal of halving the number of TB cases in the country by 2015. The firm and dedicated support from both our national and international partners have been significant in the control of TB in Timor-Leste” said Dr Martins at the launch of the country's Stop TB Strategy for 2011-2015.

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Stop TB Partnership warns of a temporary shortage of quality-assured Streptomycin

Geneva - 10 November 2010 - The Stop TB Partnership anticipates a temporary shortage of quality-assured Streptomycin. This shortage, which is also affecting other suppliers, is related to quality issues of the Active Pharmaceutical Ingredient (API) source used by one of the main Streptomycin suppliers of the Partnership's Global Drug Facility (GDF). Additionally, as major donors and technical agencies have adopted more stringent quality assurance policies, GDF is not in the short-term able to secure sufficient quantities of Streptomycin that meet the new stringent criteria.

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TB Alliance Launches First Clinical Trial of a Novel TB Drug Regimen

BERLIN, Germany — Nov. 8, 2010 In advance of the 41st Union World Conference, the Global Alliance for TB Drug Development (TB Alliance) today announced the launch of the first clinical trial to test a novel tuberculosis regimen in a new development paradigm designed to speed new treatments to patients. This novel three-drug combination shows promise to treat both drug-sensitive (DS-TB) and multidrug-resistant TB (MDR-TB), and alter the course of the TB pandemic by shortening and simplifying treatment worldwide.

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Controlling a menace in Nepal: Multi-drug resistant TB

In 1996, Nepal became the first country in the South Asia region to adopt the DOTS strategy - directly observed treatment, short-course - which among other things means a country must set up a strict daily system of recordkeeping that proves a patient takes medicine every day for six months or more. This course requires a health worker to observe a patient swallow the pills.

Nepal foundered at first. Six months after it started DOTS, a visiting team of experts reviewed its efforts and basically said it had achieved almost nothing. That inspired a massive effort in one of the poorest countries in the world, and one with some of the most challenging topography - not just the white-capped Himalayas, but also the back hills that were dotted with villages more than a day's walk from a road. The program also had to navigate around a 10-year Maoist insurgency that claimed more than 13,000 lives.

But Nepal did it - through a cadre of leaders and with WHO's guidance. By 2001, it had expanded DOTS across the nation, and today it treats TB in more than 4,000 health facilities - down to tiny health posts in the high mountains. Cure rates are at a remarkable 90 percent, and the country estimates that it is detecting 75 percent of the cases.

"Stopping TB has been a top priority for the government,'' said Dr. Kashi Kant Jha, director of the National TB Centre, who has worked in TB for more than two decades. "It's been a great challenge, and we've made lots of progress. Still, though, we have much more to do.''

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