World Health Organization Regional Office for South-East Asia

Four phases of Kala azar Elimination

 

                

1.      Preparatory Phase (Duration: Two years, 2005-2006)

 

 

The preparatory phase begins after the plan has been prepared and approved by the three countries and includes preparations for operations (including a pilot total coverage spraying operation and establishment of diagnosis and treatment facilities) in selected districts in endemic countries and monitoring (including passive and active case detection and vector monitoring). This will be useful in identifying constraints and operational difficulties. The lessons learnt during this phase can be useful in the attack phase of elimination.

The main activities proposed include the following;

*     Development/review of national policy and strategic plans. National plans should include regulation, standards and norms (Member States). The policy should cover issues relating to intercountry cooperation. Regulations should cover uniform standards relating to diagnosis and treatment, insecticides to be used in IRS, tax exemptions, and making the disease notifiable in endemic areas (Member States).

*     Development of operational plans to implement the national plan for elimination of kala-azar.

*     Development of advocacy plans that include advocacy kits, donor profiles, and highlighting the close nexus of kala-azar with HIV/AIDS, TB and leprosy. Advocacy plans should showcase the importance of elimination of kala-azar as a strategy for poverty reduction and to enhance socioeconomic development in affected areas (Member States).

*     Preparation of national plans that include budget and resource gaps (Member States).

*     Consolidation of national plans into project document for mobilizing resources (WHO/SEARO).

*     Constitution of a national coordination committee and task force/working group (Member States).

*     Signing of memorandum of understanding for intercountry cooperation and cross-border collaboration (WHO, Member States).

*     Formation of regional alliance/partners forum for resource mobilization, advocacy and assisting in periodic review for elimination of kala-azar (Member States, WHO and other partners).

*     Mobilization of additional resources (Member States and WHO).

*     Geographical information system, RS and information system for integrated vector management (WHO Support to Member States).

*     Validation of disease burden/cases of kala-azar (WHO support to Member States).

*     Development and adaptation of technical guidelines and reporting formats (WHO and Member States).

 

*     Technical guidelines (diagnosis and treatment of kala-azar and PKDL, IRS and ITNs);

*     Training package (doctors, nurses, health workers and spraying teams, supervisors);

*     Surveillance guidelines (disease surveillance, vector surveillance) ;

*     Reporting system, reporting formats ;

*     Supervisory system, quarterly monitoring and checklists;

*     Country programme and review guidelines.

 

*     Development of materials for behavioural change communication including guidelines for home care (Member States).

*     Training of personnel (doctors, health workers, staff for IRS, survey team, laboratory staff, data management staff, supervisors) with assistance from WHO.

*     Identification of research priorities and initiation of research on estimation, GIS, RS for IRS, development of new products (research on diagnostics and drugs) with assistance from WHO.

*     Establishing a system of procurement, logistics and supplies (drugs and equipment) with support from WHO.

*     Intensive implementation in selected districts (Member States).

*     Development of partnerships in the health sector (HIV/AIDS, TB, leprosy, malaria and other vector-borne diseases, nutrition, anaemia etc.) and outside the health sector (environment, poverty reduction).

 

2.      Attack Phase (Duration: Five years, 2007-2011)

 

The attack phase will begin in 2007 when the preparatory phase has ended, provided that all the tasks of the preparatory phase have been completed. This phase will include implementation and monitoring.

The main activities proposed during this phase include the following:

*     Indoor residual spraying in all the affected areas for five consecutive years in collaboration with the vector-borne disease control programme (Member States). This should be according to the agreement reached among the three endemic countries.

*     Integrated vector management including ITNs and environmental management. Monitoring expansion and coverage of ITNs (Member States).

*     Access to early diagnosis and complete treatment (Member States).

*     Passive case detection, active case detection and vector surveillance, case-based diagnosis and monthly feedback (Member States).

*     Community mobilization for vector control and for seeking early treatment (Member States).

*     Monitoring of treatment completion and analysis of treatment failure (Member States).

*     Intercountry task force meeting to review progress and exchange information (Member States and WHO).

*     Quarterly monitoring, annual review (input, process, output and outcome indicators) to be carried out by Member States. Annual reporting to WHO on an agreed reporting format.

*     Household and health facility survey once every 2-3 years (Member States with support from WHO).

*     External country evaluation (Member States with support from WHO).

*     Increasing research capacity and networking among research institutions through a research coordination mechanism (WHO and partners with Member States).

*     Active case search at least once a year in rural and urban areas (Member States).

 

3.      Consolidation Phase (Duration: Three years, 2012-2014)

 

The consolidation phase will begin when total coverage by spraying has concluded i.e. at the end of the attack phase. This phase will end after the period of three years of active surveillance has shown no increase in the incidence rate at district and subdistrict levels in endemic countries.

 

The main activities to be carried out during this phase include the following:

 

*     Limited indoor residual spraying based on geographical location of cases, and in areas with high vector density (Member States).

*     Intensified active case detection (Member States).

*     Early diagnosis and complete treatment to be sustained with focus on co-infections (Member States).

*     Treatment adherence (Member States).

*     Continued activities of the attack phase such as monitoring, research, review meetings and periodic evaluation (Member States).

 

4.      Maintenance Phase (At least 2 to 3 years)

 

During this phase, surveillance against re-introduction of kala-azar will be the responsibility of the disease control programme in the country until kala-azar is no longer a public health problem. During this phase, the case incidence at district/sub-district or upazila level should be less than 1 per 10 000 population. An international review commission should verify the achievements of the programme. Countries or affected districts in the countries where elimination targets have not been reached would require corrective measures. The maintenance phase will be followed by certification of the elimination status. The partners will decide the duration of this phase.

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