Antimicrobial resistance

The Antibiotic Resistance Workshop - Oxford Big Data Institute & Institute Pasteur, 25-26th of June 2018

The Antibiotic Resistance Workshop - University of Oxford, 25-26th of June 2018, and supported by Institute Pasteur

The Antibiotic Resistance Workshop was held in the Big Data Institute Building, University of Oxford, 25-26th of June 2018, and supported by Institute Pasteur. The aim of the workshop was to bring together microbiologist, epidemiologists and modelers working on resistance to discuss the question of “what do we need to know to make credible predictions about antibiotic resistance and decisions about interventions”, with a particular focus on Southeast Asia .

The format was a mix of presentations and intensive and rich roundtable discussion. The outcome was a way of addressing gaps in the knowledge and how to progress in light of these gaps.

The topics discussed includes:

  • AMR in South East Asia region of WHO
  • Approach to understand and predict antibiotic resistance on how to improve surveillance data and data collection
  • ABR in humans, including ESBL, multi-drug resistant bacterial infections in hospital settings and carbapenemase producing enterobacteriaceae clones
  • What needs to be known for accurate burden estimation and prediction about resistance, including the challenges of estimating the burden of AMR, how important is heterogeneity for burden estimation and when evolutionary theory matters for predictions, and when it doesn’t.
  • ABR in animals
  • What data are available, what data could be collected and how?
  • Experience from various countries, including:
    • High prevalence of ESBL producing enterobacteriacae fecal carriage within the community in Cambodia: results of the BIRDY and PEEC NIC studies.
    • Observations on the AMR situation in Cambodia
    • Antimicrobial use and antimicrobial resistance in farming systems and environmental reservoirs in Vietnam
    • Antimicrobial resistance threat in the South of Vietnam 2010-2017
    • Epidemiology and control of multi-drug resistant bacterial infections in hospitals settings, Thailand - Oxford
    • Understanding burden and drivers of drug-resistant infection in Southeast Asia, Thailand – Oxford

Beside from University of Oxford and Institute Pasteur and WHO SEARO, the workshop participants were from INSERM, University of Versailles Saint-Quentin, Harvard T.H. Chan School of Public Health, London School of Hygiene and Tropical Medicine, Thailand, Vietnam and Cambodia.

As a follow up there is a plan on writing a consensus paper based on the workshop with all participants invited as co-authors. The focus will be on ideas that emerged during the discussions, including about surveillance systems

The Antibiotic Resistance Workshop - University of Oxford, 25-26th of June 2018, and supported by Institute Pasteur
Share