Dengue Fever and Dengue Haemorrhagic Fever

Dengue is regarded as one of the most important arboviral infections in the world. Dengue fever (DF), including its variants, dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS), is caused by four antigenically distinct but related dengue viruses (DENV-1, DENV-2, DENV-3 and DENV-4), also known as serotypes, belonging to genus Flavivirus, family Flaviviridae. There exists a considerable variation within each serotype in the form of phylogenetically distinct subtypes or genotypes. Currently, each serotype has subtype/genotype as follows:
• DENV-1: Three
• DENV-2: Two (one is found in non-human primates)
• DENV-3: Four
• DENV-4: Four (one is found in non-human primates)

Informal Consultation on Case Management of Dengue, Colombo, Sri Lanka, 12-14 August 2013

There is a major concern on increase of dengue in Asia Pacific during the past decade. The WHO South-East Asia Region together with Western Pacific Region bears more than 70% of the global burden. The use of standard guidelines produced by WHO has helped in reduction of case fatality rates. As recommended by the last meeting of the Regional Technical Advisory Group for dengue in November 2012 at Bali, Indonesia , an expert consultation was organized in Colombo, Sri Lanka from 12th to 14th August 2013; to synchronize the WHO 1997 (WHO-SEARO 2011 revised) guidelines and WHO-TDR 2009 guidelines. The Expert consultation recommended to harmonize the 1997 WHO classification (2011 WHO/SEARO revised guidelines) with the WHO-TDR 2009 classification by addressing the plasma leakage (1997) as the major pathophysiology that may lead to severe disease first.

Regional Programme Review Group meeting for Lymphatic Filariasis Elimination, Dili, Timor-Leste, 25-27 June 2013

The 10th meeting of the Regional Programme Review Group (RPRG) for elimination of lymphatic filariasis (LF) was held in Dili, Timor Leste from 25th to 27th June 2013. This was attended by the members of RPRG, representatives from Centre for Neglected Tropical Diseases, Liverpool; and Glaxo-Smith-Klein (GSK). The Group reviewed the progress made by the LF endemic Member States of WHO SEA Region and requirement of Albendazole tablets (one of the drugs of the mass drug administration) for the year 2013.

fact buffet

Dengue in South-East Asia

1.3 billion people are at risk

Current situation

Reported cases of dengue

2.4 million reported cases between 2000-2011

Reported cases
pdf, 141kb

Dengue fatality rate

<1%case fatality rate

Dengue analysis in South-East Asia
pdf, 12kb

Joint SEARO-TDR Small Grants Programme (2014)

The World Health Organization Regional Office for South-East Asia (SEARO), in collaboration with the Special Programme for Research and Training in Tropical Diseases (TDR), is pleased to announce the 2014 call for applications for the Joint SEARO/TDR small grants scheme for implementation research in infectious diseases of poverty.

Revised Closing Date is 30 June 2014

Contact us:
Dr Ahmed Jamsheed Mohamed

World Health Organization
Regional Office for South-East Asia
World Health House
Indraprastha Estate
Mahatma Gandhi Marg
New Delhi 110 002, India
Telephone: +91-11-23370804, 23370809-11